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| Association of sex, age and ABO-Rh(D) type with unexpected antibodies among multitransfused thalassemia patients in Bikaner, Rajasthan, India |
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| DOI：10.46701/APJBG.2018032018107 |
| KeyWord:thalassemia major, transfusion therapy, alloimmunization, unexpected antibodies |
| Author | Institution |
| Shailendra Vashistha |
Department of Immuno-Haematology & Transfusion Medicine, Sardar Patel Medical College & Associated Group of Hospitals, Bikaner 334001, Rajasthan, India |
| Kunal Purohit |
Department of Immuno-Haematology & Transfusion Medicine, Sardar Patel Medical College & Associated Group of Hospitals, Bikaner 334001, Rajasthan, India |
| Devraj Arya |
Department of Immuno-Haematology & Transfusion Medicine, Sardar Patel Medical College & Associated Group of Hospitals, Bikaner 334001, Rajasthan, India |
| Arun Bharti |
Department of Immuno-Haematology & Transfusion Medicine, Sardar Patel Medical College & Associated Group of Hospitals, Bikaner 334001, Rajasthan, India |
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| Download times: 2013 |
| Abstract: |
| The thalassemia has become a sensitive issue for clinical and public health owing to the morbidity and mortality caused and potential risks associated with multiple transfusions. Here, a blood bank based cross sectional analytical study was carried out during the period of three months from January 2017 to March 2017, among transfusion dependent beta thalassemia major patients. ABO-Rh(D) blood grouping and screening for unexpected red cell antibodies (other than anti-A and anti-B antibodies) were performed on a Immucor Galileo Neo System (fully automated immunohematology analyzer). Out of 56 patients, 37 (66%) were males and 19 (34%) were females with a male to female ratio of 1.95:1. Two cases (3.6%) were detected positive by antibody screening. Alloimmunization was statistically analyzed on the basis of age, sex and subjects' ABO-Rh blood group. This study underlines the need for unexpected antibody screening among thalassemic patients receiving blood transfusion therapy. |
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